A great methodology for catalytic pyrrole synthesis by the Master of Atom Economy, Prof. Trost. This method can lead to useful pyrrole derivatives. The 'Molecular Lego'-style chemistry will prove to be important foe better and more efficient syntheses.
*Diagram from J. Am. Chem. Soc. Webpage
Reference:
An Atom-Economic Synthesis of Nitrogen Heterocycles from Alkynes
Barry M. Trost*, Jean-Philip Lumb, and Joseph M. Azzarelli
J. Am. Chem. Soc., Article ASAP
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