Tuesday 4 January 2011

Textbook reaction with a twist




A nice demonstration of the classic 'synthetic logic' of heterocycles. This author makes useful imidazole derivatives with Zinc Triflate as the catalyst.

Reference:
A novel Zn-catalyzed hydroamination of propargylamides: a general synthesis of di- and tri-substituted imidazoles

Anahit Pews-Davtyan and Matthias Beller
Chem. Commun., 2011, Advance Article

DOI: 10.1039/C0CC04625F

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